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Yonghong Liang Ph.D. Curriculum vitae

Yonghong Liang Ph.D. Curriculum vitae

Lintho tse khōlō tse atlehileng

Phihlelo ea Lipatlisiso

  • Sep. 2006-hona joale Ho sebetsa ho Ph.D (Organic Chemistry)
    Projects
    1. Thuto e utloahalang ea ho sebelisana pakeng tsa dapivirine (TMC120) le HIV-1 reverse transcriptase
    2. Kamano e mengata ea likamano-liketsahalo ho ithuta ka benzyl e nkiloeng ka diarylpyrimidines
    3. Tlhahlobo, lipatlisiso le lipalo tsa SAR tsa diarylpyrimidine ea α kapa β naphthyl e nkiloeng e le li-non-nucleoside inhibitors tsa HIV-1 reverse transcriptase
    4. Ho qaptjoa le ho qaptjoa ha DABO e le li-inhibitors tse peli tsa HIV-1 reverse transcriptase le integrase

  • 2003-2006 Motlatsi oa Mosuoe
    Projects
    1. Phallo ea proton-intramolecular proton bakeng sa 2-hydroxybenzophenone, 8-hydroxy-4H-naphthalen-1-one, 5-hydroxy-4, 5-naphthoquinone, 1-hydroxy-9, 10-anthraquione, 7-Hydroxy -1-indenone, 5, 8-dihydroxy-1, 4-naphthoquinone), 4, 9-dihydroxyperylene-3, 10-quinone le hypocrellin A e ne e ithutoa ka mekhoa ea lithuto.
    2. Puso ea mobu e tsamaisoang ke proton ea inermolecular in the complexes ea 5-hydroxyisoxazole-metsi, DNA (RNA) base dimer le base-N-methylformamide e ne e etsoa ka mekhoa ea DFT.
    2002-2003 Kamano ea moralo oa thepa-thepa ho thepa ea physicochemical ea ketone le aldehyde

Awards

Setereke sa Hunan sehlabelo sa Master Master, 2008

Publications

1. Liang, YH; Chen, FE ONIOM DFT / PM3 lipalo mabapi le ho sebelisana pakeng tsa HIV-1 reverse transcriptase, thuto ea thuto. Discov ea lithethefatsi. Ther. 2007, 1, 57-60.

2. Liang, YH; Chen, FE QSAR liphuputso tsa diarylpyrimidines khahlanong le HIV-1 reverse transcriptase mofuta oa mofuta o mong le o mong le oa mutant. EUR. J. Med. Chem. 2009, 44, 625-631

3. Liang, YH; Feng, XQ; Zeng, ZS; Chen, FE; Balzarini, J.; Pannecouque, C ;; De Clercq, E. Design, Synthesis, le SAR ea Naphthyl-Substituted Diarylpyrimidines e le Non-Nucleoside Inhibitors ea HIV-1 Reverse Transcriptase. ChemMedChem 2009, 4, 1537-1545.

4. Feng, XQ; Liang, YH; Zeng, ZS; Chen, FE; Balzarini, J.; Pannecouque, C ;; De Clercq, E. Ho Fetoha ha Mekhoa ea DAPY Mantsoe a nang le Ketsahalo e matla ea Anti-HIV-1. ChemMedChem 2009, 4, 219.

5. Zeng, ZS; Liang, YH; Feng, XQ; Chen, FE; Balzarini, J.; Pannecouque, C ;; De Clercq, E. Lead optimization ea diarylpyrimidines e le inhibitors ea non-nucleoside HIV-1 reverse transcriptase, ChemMedChem 2010, e amohelehang.

6. Liang, YH; Yi, PG Thuto ea thuto ka mokhoa oa ho fetola, ho matlafatsa le ho fetisa phallo ea proton ea alkannin. Li-Chemical Physics Letters, 2007, 438, 173.

7. Liang, YH; Yi, PG; Peng, HL Thuto ea thuto ea moralo, matla le intramolecular transfer of hypocrellin A. Liphoofolo tsa Liphoofolo tsa Letsoho, 2008, 466, 6-10.

8. Liang, YH; Yi, PG. Cao, CZ Thuto ea ho ithuta ka motsoako oa motone oa proton o fetisitsoeng ho 5-hydroxyisoxazole. Journal ea Boleng ba Melemo: Theochem, 2005, 729, 163-167.

9. Yi, PG .; Liang, YH; Cao, CZ Proton e entramolecular kapa hydrogen-atom e fetisetsoa fatše le linaheng tse thabisang tsa 2-hydroxybenzophenone: Thuto ea thuto. Lik'hemik'hale tsa 'mele, 2005, 319, 297.

10. Yi, PG .; Liang, YH Liphuputso tsa khopolo ea ho kopanya likhohlano le liphello tse nyane tsa phetoho ea proton e entsoeng fatše le linaheng tse thabileng. Lik'hemik'hale tsa 'mele, 2006, 322, 382.

11. Yi, PG .; Liang, YH Tang, ZQ Thuto ea thuto ea phetoho ea li-proton e fetisoang ho 5-hydroxyisoxazole-water complexes. Meriana ea Liphemik'hale, 2006, 2006, 322, 387.

12. Liang, YH; Zeng, ZS; Feng, XQ; Chen, FE; Balzarini, J.; Pannecouque, C ;; De Clercq, E. Parallel Synthesis le Likokoana-hloko Tlhahlobo ea Diarylpyrimidines le Ketsahalo e matla ea Anti-HIV-1. Med. Chem. 2010, 18 (13), 4601.

13. Liang, YH; Zeng, ZS; Feng, XQ; Chen, FE; Balzarini, J.; Pannecouque, C ;; De Clercq, E. Moqapi oa DABO e le li-inhibitor tse peli tsa HIV-1 reverse transcriptase le integrase. J. Med. Chem.

14. Chen, FE, Liang, YH Khatelo-pele ea morao-rao khahlanong le likokoana-hloko tse ngata tse khahlanong le AIDS, Tsoelo-pele ho Chemistry ea Bongaka (8), Peng, SQ Ed., 2011, 167.

15. Chen, FE, Liang, YH, Zeng, ZS PCT / CN2009 / 075931.

16. Zeng, ZS, Liang, YH, Zhang, JY, Xiong, JC China Patent ,, CN201110070027.4

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